sadamoto laboratory

お茶の水女子大ロゴ

貞許　礼子　Reiko SADAMOTO

　　　　　　　　　　　　　　　　　　　　　→経歴

研究業績

  1. ITO Takaomi, SADAMOTO Reiko, NARUCHI Kentaro, TOGAME Hiroko, TAKEMOTO Hiroshi, KONDO Hirosato, NISHIMURA Shin-Ichiro, Highly oriented recombinant glycosyltransferases: Site-specific immobilization of unstable membrane proteins by using Staphylococcus aureus sortase A, Biochemistry, 49(11), 2604-2614, 2010.
  2. MATSUSHITA Takahiko, SADAMOTO Reiko, OHYABU Naoki, NAKATA Hideki, FUMOTO Masataka, FUJITANI Naoki, TAKEGAWA Yasuhiro, SAKAMOTO Takeshi, KUROGOCHI Masaki, HINOU Hiroshi, SHIMIZU Hiroki, ITO Takaomi, NARUCHI Kentarou, TOGAME Hiroko, TAKEMOTO Hiroshi, KONDO Hirosato, NISHIMURA Shin-Ichiro, Functional neoglycopeptides: Synthesis and characterization of a new class of MUC1 glycoprotein models having core 2-based O-glycan and complex-type N-glycan chains, Biochemistry, 48(46),11117-11133, 2009.
  3. SADAMOTO Reiko, MATSUBAYASHI Takeshi, SHIMIZU Masataka, UEDA Taichi, KOSHIDA  Shuhei, KODA Tashiaki, NISHIMURA Shin-Ichiro, Bacterial surface engineering utilizing glucosamine phosphate derivatives as cell wall precursor surrogates, Chem. Eur. J., 14(33),10192-10195, 2008.
  4. MATSUBARA Naoki, OIWA Kei, HOHSAKA Takahiro, SADAMOTO Reiko, NIIKURA Kenichi, FUKUHARA Norio, TAKIMOTO Akio, KONDO Hirosato, NISHIMURA Shin-Ichiro, Molecular design of glycoprotein mimetics: Glyco-blotting by engineered proteins with an oxylamino-functionalized amino acid residue, Chem. Eur. J., 11(23), 6974-6981, 2005.
  5. FURUIKE Tetsuya, SADAMOTO Reiko, NIIKURA Kenichi, MONDE Kenji, SAKAIRI Nobuo, NISHIMURA Shin-Ichiro, Chemical and enzymatic synthesis of glycocluster having seven sialyl Lewis X arrays using b-cyclodextrin as a key scaffold material, Tetrahedron, 61(7), 1737-1742, 2005.
  6. UEDA Taichi, FENG Fei, SADAMOTO Reiko, NIIKURA Kenichi, MONDE Kenji, NISHIMURA Shin-Ichiro, Synthesis of 4-fluorinated UDP-MurNAc pentapeptide as an inhibitor of bacterial growth, Org. Lett., 6(11), 1753-1756, 2004.
  7. SATO Masaaki, FURUIKE Tetsuya, SADAMOTO Reiko, FUJITANI Naoki, NAKAHARA Taku, NIIKURA Kenichi, MONDE Kenji, KONDO Hirosato, NISHIMURA Shin-Ichiro, Glycoinsulins: dendritic sialyloligosaccharide-displaying insulins showing a prolonged blood-sugar-lowering activity, J. Am. Chem. Soc., 126(43), 14013-14022, 2004.
  8. SATO Masaaki, SADAMOTO Reiko, NIIKURA Kenichi, MONDE Kenji, KONDO Hirosato, NISHIMURA Shin-Ichiro, Site-specific introduction of sialic acid into insulin, Angew. Chem., Int. Ed., 43(12), 1516-1520, 2004.
  9. SADAMOTO Reiko, NIIKURA Kenichi, UEDA Taichi, MONDE Kenji, FUKUHARA Norio, NISHIMURA Shin-Ichiro, Control of bacteria adhesion by cell-wall engineering, J. Am. Chem. Soc., 126(12), 3755-3761, 2004.
  10. NISHIMURA Shin-Ichiro, NAGAHORI Noriko, SADAMOTO Reiko, MONDE Kenji, NIIKURA Kenichi, Artificial golgi apparatus: direct monitoring of glycosylation reactions on automated glycosynthesizer, ACS Symp. Ser., 873, 113-124, 2004.
  11. NIIKURA Kenichi, OSUGA Noriko, NAGOHORI Noriko, SADAMOTO Reiko, SHIONO Masamichi, IWASAKI Norimasa, MONDE Kenji, MINAMI Akiko, NISHIMURA Shin-Ichiro, Fluorescent glyconanoparticles as a sensitive device to monitor sugar-involving molecular events, Polym. J., 36(3), 209-218, 2004.
  12. FENG Fei, OKUYAMA Kiyoshi, NIIKURA Kenichi, OHTA Takashi, SADAMOTO Reiko, MONDE Kenji, NOGUCHI Toshitada, NISHIMURA Shin-Ichiro, Chemo-enzymatic synthesis of fluorinated 2-N-acetamidosugar nucleotides using UDP-GlcNAc pyrophosphorylase, Org. Biomol. Chem., 2(11), 1617-1623, 2004.
  13. SADAMOTO Reiko, NIIKURA Kenichi, MONDE Kenji, NISHIMURA Shin-Ichiro, Cell wall engineering of living bacteria through biosynthesis, Methods Enzymol., 362, 273-286, 2003.
  14. OHTA Takashi, MIURA Nobuaki, FUJITANI Naoki, NAKAJIMA Fumio, NIIKURA Kenichi, SADAMOTO Reiko, GUO Chao-Tan, SUZIKI Takashi, SUZUKI Yasuo, MONDE Kenji, NISHIMURA Shin-Ichiro, Glycotentacles: Synthesis of cyclic glycopeptides, toward a tailored blocker of influenza virus hemagglutinin, Angew. Chem., Int. Ed., 42(42), 5186-5189, 2003.
  15. NAGAHORI Noriko, NIIKURA Kenichi, SADAMOTO Reiko, TANIGUCHI Masahiro, YAMAGISHI Akihiko, MONDE Kenji, NISHIMURA Shin-Ichiro,  Glycosyltransferase microarray displayed on the glycolipid LB membrane, Adv. Syn. Catal., 345(6+7), 729-734, 2003.
  16. NAGAHORI Noriko, NIIKURA Kenichi, SADAMOTO Reiko, MONDE Kenji, NISHIMURA Shin-Ichiro, Synthesis of photopolymerizable glycolipids and their application as scaffolds to immobilize proteins with a micron-sized pattern, Aust. J. Chem., 56(6), 567-576, 2003.
  17. LIU Haitian, RITTER Tomas K., SADAMOTO Reiko, SEARS Pamela S., WU Min, WONG Chi-Huey, Acceptor specificity and inhibition of the bacterial cell-wall glycosyltransferase MurG, ChemBioChem, 4(7), 603-609, 2003.
  18. SADAMOTO Reiko, NIIKURA Kenichi, SEARS Pamela S., LIU Haitian, WONG Chi-Huey, SUKSOMCHEEP Akarat, TOMITA Fusao, MONDE Kenji, NISHIMURA Shin-Ichiro, Cell-wall engineering of living bacteria, J. Am. Chem. Soc., 124(31), 9018-9019, 2002.
  19. LIU Haitian, SADAMOTO Reiko, SEARS Pamela S., WONG Chi-Huey, An efficient chemoenzymatic strategy for the synthesis of wild-type and vancomycin-resistant bacterial cell-wall Precursors: UDP-N-acetylmuramyl-peptides, J. Am. Chem. Soc., 123(40), 9916-9917, 2001.
  20. JIANG Dong-Lin, SADAMOTO Reiko, TOMIOKA Nobuyuki, AIDA Takuzo, Molecular design and functions of dendrimer porphyrins, 高分子論文集, 54(10), 674-683, 1997.
  21. SADAMOTO Reiko, UEDONO Akira, KAWANO T., TANIGAWA Shouchiro, KOSAKA Yozo, URYU Toshiyuki, Free volumes in nematic and smectic liquid-crystalline polymers probed by positron annihilation, J. Polym. Sci. B., 34(9), 1659-1664, 1996.
  22. SADAMOTO Reiko, TOMIOKA Nobuyuki, AIDA Takuzo, Photoinduced electron transfer reactions through dendrimer architecture, J. Am. Chem. Soc., 118(16), 3978-3979, 1996.
  23. UEDONO Akira, SADAMOTO Reiko, KAWANO T., TANIGAWA Shoichiro, URYU Toshiyuki, Free volumes in liquid-crystalline main-chain polymer probed by positron annihilation, J. Polym. Sci. B., 33(6), 891-897, 1995.
  24. NOMURA K., HANAI T., SADAMOTO Reiko, UJIHIRA Yusuke, RYUO T., TANNO M., Conversion electron Moessbauer spectroscopic study of YIG substituted with Bi, Ti, Ga and La, Hyperfine Interactions, 84(1-4), 421-426, 1994.
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総説・著書等

  1. 貞許 礼子, 生合成経路を用いたバクテリア細胞壁への分子提示法, バイオインダストリー, 21(2)37-42 , 2010.
  2. SADAMOTO Reiko, NISHIMURA Shin-Ichiro, Glycosylation Engineering of Glycoproteins, Glycoscience,2nd Ed., Fraser-Reid et al. (Ed.), Springer Verlag, 1859-1871, 2008.
  3. 貞許 礼子, 数々の研究室を渡り歩いて, グローイングポリマー, 高分子, 54(12), 2005.
  4. SADAMOTO Reiko, NISHIMURA Shin-Ichiro, Chemo-biological approach to modification of the bacterial cell wall. Handbook of Carbohydrate Engineering, YAREMA Kevin S., (Ed.) CRC Press LLC, 495-505, 2005.
  5. SADAMOTO Reiko., Artificial modification of bacterial surface with cell-wall engineering. Trends in Glycoscience and Glycotechnology, 17(95), 97-105, 2005.
  6. 貞許 礼子, 糖鎖誘導体を用いたバクテリアの人工機能化, 糖鎖科学の新展開, -機能解明・次世代型材料・医薬品開発に向けて-, エヌ・ティー・エス, 426-435, 2005.
  7. 貞許 礼子, バクテリア表層化学改変法を用いたバクテリア製剤の開発. バイオロジクス-生体由来物質を用いた製品開発-,ポリマーフロンティア21シリーズ, 高分子学会編, 23, 69-91, 2004.
  8. JIANG Dong-Lin, SADAMOTO Reiko, TOMIOKA Nobuyuki, AIDA Takuzo, Dendrimer porphyrins for biomimetic applications. Hyper-Structured Molecules I: Chemistry, Physics and Applications, 63-73, 1999.
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招待講演

  1. Glyco TOKYO 2009シンポジウム（東京）
    2009年11月14日
    ケミカルバイオロジー手法によるバクテリア表層への特異的分子提示法
    貞許 礼子
  2. 第9回東日本スクリプス会（東京）
    2007年11月10日　
    生命分子機能学（塩野義）研究室-北海道大学における寄附講座-の研究紹介
    貞許 礼子
  3. 第56回高分子討論会併設 第4回国際交流シンポジウム-海外へはばたく女性研究者-（名古屋）
    2007年9月19日
    米国での2年間
    貞許 礼子
  4. 新化学発展協会講演会 受賞研究報告会（東京）
    2006年11月17日
    生きたバクテリア表層の人工修飾
    貞許 礼子
  5. 立命館大学理工学研究所主催　光生命科学研究セミナー（立命館大学　びわこ・くさつキャンパス）
    2006年4月21日
    糖鎖で薬を創る
    貞許 礼子
  6. 東工大　BioLipid研究会（箱根）
    2004年10月1日
    バクテリア表層修飾による新機能開発
    貞許 礼子
  7. The 21st COE young scientist network symposium: toward a fusion of bioscience and nanotechnology（Hokkaido Univ. Creative Research Initiative “Sosei”）
    2004年8月6日
    Bacterial Cell-Wall Engineering: Chemical Modifications of Biopolymer
    SADAMOTO Reiko.
  8. 04-1ポリマーフロンティア21（東京工業大学百年記念館）
    2004年4月23日
    バクテリア表層化学改変法を用いたバクテリア製剤の開発
    貞許 礼子
  9. Glyco TOKYO21シンポジウム「若手研究者が語るポストゲノム時代の糖鎖研究」（東京）
    2001年11月
    貞許 礼子

 

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お茶の水女子大学　　お茶大アカデミック・プロダクション　　貞許研究室